Type 2 diabetes is the most common type of diabetes accounting for 90 to 95 percent of all cases in 2015 more than 23 million people in the united states had diagnosed diabetes and an additional 7 million people likely had undiagnosed diabetes. Type 2 diabetes t2d is the result of interaction between environmental factors and a strong hereditary component we review the heritability of t2d as well as the history of genetic and genomic research in this area very few t2d risk genes were identified . Diabetes is a complex condition several factors must come together for you to develop type 2 diabetes for example obesity and a sedentary lifestyle play a role genetics can also influence . New insights from monogenic diabetes for common type 2 diabetes divya sri priyanka tallapragada seema bhaskar and giriraj r chandak genomic research on complex diseases laboratory council of scientific and industrial research centre for cellular and molecular biology hyderabad india. Sequencing data from two large scale studies show that most of the genetic variation influencing the risk of type 2 diabetes involves common alleles and is found in regions previously identified
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